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KMID : 0878220110230030391
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Journal of Sasang Constitutional Medicine
2011 Volume.23 No. 3 p.391 ~ p.401
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Effect of Taeeumjoweetang on the Body Composition, Serum Lipid Level and Antioxidant Enzyme Activity of Obese Female College Students
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Kim Hye-Ju
Ahn Hong-Seok
Oh Eun-Ha
Kim Young-Locke
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Abstract
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Objectives: Though the eating habits have improved and the living method has become convenient according to the economic growth thanks to the modern industrialization, because of the lack of exercise, obesity, wrong eating habits and stress etc, various symptoms of disease of adults are on the rise. This is the phenomenon that happens as the eating life has become life in the West along with the inundation of the western culture in our society. In this perspective, there has been many various clinical research that’s been proceeded so far about the physical constitution and obesity, but there has been little research on the objective analysis of the clinical research about the alimentotherapy using taeeumjoweetang.
Methods: In this research we have checked the weights, fat rates, fat weight, abdominal fat rate, blood pressure, and BMI over the objects of the women that were diagnosed as lunisolar system as their physical constitution, and assessed the paramecium lipid, in-blood antioxidation enzyme and the damage of oxidization in the urine by physical constitution-specific of the body shapes that were determined by BMI. The statistical analysis of the current research was processed by using of SPSS 17.0 program. We have figure out statistical amounts such as the arithmetic average, average deviation rate and percentage number. Fro the verification of he significancy of each elements, we have used the paired t-test, ANOVA, Chi-square test at the level of p<0.05.
Results and Conclusions :Their characteristics are age 21.20±1.35, height 160.30±6.11cm, weight 64.66±8.72kg, fat rates are 35.97±4.87%, fat amount 23.40±5.48, abdominal fat rate 0.823±0.03, BMI 25.12±2.79kg/m², and systolic blood pressure 111.60±10.28mmHg and diastolic blood pressure 68.60±7.43mmHg and we have let them take the medicine twice a day for 8 weeks. The clinical result for the Cholesterol, Triglyceride, HDL-cholesterol, LDL-cholesterol, SGOT, SGPT, of the object people was that for the function of the liver, the result of the SGOT and SGPT test was 17.16±3.05, 15.00±2.99IU/L, which was a decrease, and had statistical meaning, but for the SGOT, though the figure reduced to 11.92±4.61, 10.80±3.07, it had no statistical meaning. For the whole cholesterol level, the figure reduced to 169.00±19.95, 160.08±22.52 mg/dL and had statistical significance(p<0.05). Neuter fat number, Triglyceride has slightly increased to 67.52±36.32, 68.08±47.33 mg/dL but did not have any statistical meaning. The antioxdant enzyme marker standard marker, SOD has increased to 2.52±0.73, 2.86±0.60U/ml, and had statistical significance(p<0.01). Catalase also increased by 0.63±0.18, 1.07±0.25mmol/ml and had statistical meaning(p<0.01). GPx also increased to 204.76±32.64 nmol/ml and had statistical meaning(p<0.01). But, for the Total antioxidant, though it has raised to 1.51±0.26, 1.57±0.17nmol/㎕, it did not have any statistical meaning. MDA of oxidative stress marker has decreased to 1.70±0.68㎍/㎖, 1.21±0.50㎍/m and had statistical significance(p<0.01). 8-OHdG also decreased 3.35±0.95ng/ml, 2.21±0.50ng/ml and had statistical meaning(p<0.01). In this research, we have analyzed the various markers relating to BFM and changes in oxidative enzyme in blood by takingtaeeumjoweetang. Taeeumjoweetang has the positive effect on inbody antioxidant system and reducing the content of cholesterol, which is proven to help losing weight and improving hyperlipidemia statistically. With this research, we hope to improve the lifestyle of those who are either obese or need to manage their dietary habits, and also to become the touchstone of integrating Oriental Medicine with the science of food & nutrition.
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KEYWORD
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Obesity, Blood lipids, Taeeumjoweetang, Tae-eumin, Antioxdants, Damage of oxidization
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